Is PRP Hair Treatment a Permanent Solution

Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentration of platelet-rich plasma protein that is derived from an individual’s blood. The blood is centrifuged to remove red blood cells and separate plasma. This concentrated blood plasma contains several growth factors and cytokines that stimulate the healing of soft tissues. In dermatology, it is effectively said to treat androgenic alopecia. PRP for hair loss is being hyped today due to its high PRP hair treatment success rate. PRP injections are said to trigger natural hair growth and maintain growth by increasing blood supply to the hair follicle. In the same light, we’ll discuss whether or not PRP hair treatment is a permanent solution. Is PRP Hair Loss Treatment Permanent? PRP treatment is not a permanent cure for hair loss; instead, it’s a treatment that helps to slow the progression of hair loss and promote the growth of new hair. No doubt it prevents hair loss, but an individual may need multiple PRP sessions for hair growth and maintenance. It temporarily restores the ability of hair follicles to grow, and with multiple sessions, one can keep up the same rate.   Hence, PRP cannot be considered a permanent or one-time solution. It does provide better results than minoxidil and, thus, can be considered a better alternative. The results of PRP treatment last for 1-3 years, depending on the individual’s condition. The platelet-rich plasma is drawn up into a syringe and then injected into the client’s scalp. This leads to increased hair growth. The growth factor mechanism of PRP therapy: Platelet granules release growth hormones like,
  • Transforming growth factor (TGF): Assists the development of the matrix between cells
  • Platelet-derived growth factor (PDGF): stimulates skin and blood vessel growth
  • Vascular endothelial growth factor (VEGF): helps the formation of blood vessels
  • Epidermal growth factor (EGF): increases cell growth and formation of blood vessels
  • Insulin-like growth factor (IGF): regulates healthy and normal cell physiology
  • Fibroblast growth factor (FGF): helps specialised cell formation
These growth factors act on stem cells in the bulge area of the follicles, stimulating the development of new follicles and promoting neovascularization. In fact, primitive stem cells that come from the ectoderm are found in the bulge area. These stem cells make epidermal cells and sebaceous glands.   At the dermal papilla of the matrix, you can find germinating cells that come from the mesenchyme. Interactions between these two types of cells, as well as with growth factors that bind to them (PDGF, TGF, and VEGF), start the hair’s growth phase and lead to the formation of the follicular unit.   Hence, to summarise, PRP contains proteins that serve several functions, like: Helping blood clots and encouraging cell growth So during the hair cycle, the dermal papilla cells live longer because PRP turns on anti-apoptotic regulators like the Bcl-2 protein and Akt signalling. With PRP treatment, the FGF-7/-catenin signalling pathways may be turned on, which may help hair grow by causing follicular stem cells to change and by extending the anagen phase of the hair growth cycle.   It also seems to make the perifollicular vascular plexus bigger by making the levels of VEGF and PDGF go up, which can make blood vessels grow. Hence, it shows the positive effects of PRP as a hair loss treatment. Though not permanent, PRP treatment is a promising solution. This treatment is also combined with hair transplant procedures to yield better results and quick healing. The anti-apoptotic effects of activated PRP have been suggested to contribute to hair growth.   If you are looking for an advanced PRP hair treatment in South India, Adgrohair is where you should consider going to get a PRP Pro + done, which is a recent advancement in regenerative medicine that practises world-class hair restoration treatments. They provide complimentary PRP therapy or individual PRP therapy, as required.

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